We invite contributions which discuss possible connections between the astronomical forcing and transitions in the dynamics of the Earth system, including global: extinctions, anoxia, global glaciations, regime changes, and more regional events. We aim at bringing together contributions which are either based on observations, on theoretical arguments, or both. We welcome submissions which explore the climate system response to orbital forcing, and that analyse the stability of these relationships under different climate regimes or across evolving climate states. This includes the Cenozoic (e.g. mid Pleistocene transition, Pliocene-Pleistocene transition, Miocene vs Pliocene), old the other periods of the Phaneorozoic and before. We also particularly welcome submissions which explore the effects of astronomical forcing on expression and amplification of millennial variability.