Interactions between Antarctic Ice Sheet (AIS), oceans and the atmosphere can dictate changes in ice geometry, ocean circulation patterns, hydrological cycles, and global sea level, all of which feed back into the earth system. To better predict how these processes might change in the future, it is useful to investigate the behaviour of the AIS and the surrounding Southern Ocean during critical Cenozoic climate intervals. This session targets studies that reconstruct changes to the AIS and its adjacent ocean (such as ice sheet stability, sea ice cover, surface/deep water circulation, meltwater/precipitation supply) across past climates on various timescales (such as the Miocene Climatic Optimum, or Quaternary glacial cycles). We welcome multidisciplinary contributions that leverage Antarctica-proximal sediment archives, as well as ice sheet-climate modelling. Studies focusing on novel methodological developments and applications for reconstructing polar paleoclimate are strongly encouraged.